What is Glucophage SR?
Glucophage SR, commonly known as Metformin SR, is an oral diabetes medication that helps control blood sugar levels. It’s mainly prescribed for individuals with type 2 diabetes mellitus. This extended-release form of metformin is designed to release the medication slowly over time, which helps in maintaining a consistent level of the drug in the bloodstream, reducing dosage frequency, and minimizing side effects.
Mechanism of Action
Glucophage SR works by decreasing hepatic glucose production, decreasing intestinal absorption of glucose, and improving insulin sensitivity by increasing peripheral glucose uptake and utilization. This multi-faceted approach helps in effectively lowering blood glucose levels in patients with type 2 diabetes.
Indications for Use
– Type 2 Diabetes Mellitus: Glucophage SR is primarily prescribed for managing type 2 diabetes, especially when diet and exercise alone are not sufficient to control blood sugar levels.
– Insulin Resistance: It may also be used in cases of insulin resistance where the body does not respond adequately to insulin.
– Polycystic Ovary Syndrome (PCOS): Though not officially approved, some healthcare providers prescribe Glucophage SR for managing symptoms associated with PCOS.
How to Use Glucophage SR
Glucophage SR should be taken as prescribed by a healthcare professional. The extended-release tablets are usually taken once daily with the evening meal. It’s crucial to swallow the tablets whole and not crush or chew them to preserve the extended-release mechanism.
Recommended Dosages
– Starting Dose: Typically, the initial dose is 500 mg once daily with the evening meal.
– Dosage Adjustment: The dosage may be gradually increased by 500 mg increments weekly, based on blood glucose levels.
– Maximum Dose: The maximum recommended dose is 2000 mg per day.
Possible Side Effects
Like all medications, Glucophage SR may cause side effects. Common side effects include:
– Gastrointestinal Issues: Nausea, vomiting, diarrhea, and stomach discomfort.
– Taste Disturbance: Some patients report a metallic taste in the mouth.
– Lactic Acidosis: Though rare, lactic acidosis is a serious side effect that requires immediate medical attention. Symptoms include unusual muscle pain, trouble breathing, stomach pain, dizziness, and feeling cold.
Comments from Healthcare Professionals
Dr. Emily Carter, an endocrinologist, says, “Glucophage SR is a cornerstone treatment for type 2 diabetes. Its extended-release formulation helps in better compliance due to reduced dosing frequency and lower risk of gastrointestinal side effects compared to immediate-release forms.”
Recommendations for Use
– Monitoring: Regular monitoring of blood glucose levels is essential while on Glucophage SR to ensure effectiveness and adjust dosages as needed.
– Diet and Exercise: Incorporate a balanced diet and regular exercise as part of your diabetes management plan.
– Alcohol Consumption: Limit alcohol intake as it can increase the risk of lactic acidosis.
Where to Purchase Glucophage SR
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Additional Information
– Interactions: Be aware of potential drug interactions with medications like diuretics, corticosteroids, and other diabetes medications.
– Storage: Store Glucophage SR at room temperature away from moisture and heat.
Infographic: Glucophage SR Quick Facts
– Class: Biguanide
– Formulation: Extended-release
– Primary Use: Type 2 Diabetes
– Common Side Effects: GI upset, metallic taste
– Serious Risk: Lactic Acidosis
For more detailed information, consult reputable sources such as the American Diabetes Association or the National Institute of Diabetes and Digestive and Kidney Diseases. Always discuss with your healthcare provider before making changes to your medication regimen.
